There are four changes to the Southampton side heavily beaten by Chelsea last weekend, as Broja, Valery, Lyanco and Perraud are drafted into the starting XI. That sees Armstrong, Adams, Salisu and Livramento relegated to the bench by coach Ralph Hasenhuttl.
SUBS: Bernd Leno, Nicolas Pepe, Emile Smith Rowe, Rob Holding, Miguel Azeez, Zak Swanson, Mohamed Elneny, Mazeed Ogungbo, Omari Hutchinson.
ARSENAL (4-3-3): Aaron Ramsdale; Cedric Soares, Ben White, Gabriel Magalhaes, Nuno Tavares; Albert Sambi Lokonga, Granit Xhaka, Martin Odegaard; Bukayo Saka, Eddie Nketiah, Gabriel Martinelli.
SUBS: Willy Caballero, Che Adams, Shane Long, Nathan Tella, Jack Stephens, Mohammed Salisu, Nathan Redmond, Valentino Livramento, Adam Armstrong.